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GenderFeminine & Masculine
ContributorContrib.anonymous on 4/21/2006
Meaning & History
From the traditionally Spanish habitation surname derived from any of the numerous places named Santa ANA
Its usage may be due to popular Mexican-American musician Carlos Santana, founder of the Latin rock band Santana. On the Fox television show 'Glee', one of the protagonists is named Santana Lopez, portrayed by actress Naya Rivera.