Namesakes
Biblical Characters:
1 character
Luke (m) Luke 1:2 
Fictional Characters from Books:
1 character
Luke 1975 Eight Days of Luke
Fictional Characters from Movies:
1 character, 1 hero
Luke Jackson 1967 Cool Hand Luke
Luke Skywalker 1977 Star Wars
Fictional Characters from Song Titles:
1 character
(character) Luke 1991 The Gospel According To Luke
Fictional Characters from Television:
5 characters
Luke Duke 1979 The Dukes of Hazzard
Luke Brower 1985 Growing Pains
Luke Boyd 2000 Waking the Dead
Luke Danes 2000 Gilmore Girls
Luke Ward 2003 The O.C.
Hall-of-Famers:
1 baseball
(baseball) Luke Appling 1964
Notable Actors and Entertainers:
6 actors
Luke Perry 1966-2019
Luke Wilson 1971-
Luke Mably 1976-
Luke Evans 1979-
Luke Kleintank 1990-
Luke Benward 1995-
Notable Athletes:
5 rugby, 2 darts, 2 soccer
(rugby) Luke Charteris 1983-
(rugby) Luke Romano 1986-
(rugby) Luke McLean 1987-
(rugby) Luke Fitzgerald 1987-
(rugby) Aaron Smith (a.k.a. Luke) 1988-
(soccer) Luke McCullough 1994-
(darts) Luke Humphries 1995-
(soccer) Luke Shaw 1995-
(darts) Luke "The Nuke" Littler 2007-
Olympic Medalists:
2 gold, 1 silver
(gold) Lucious Jackson (a.k.a. Luke) 1964 basketball
(silver) Luke Patience 2012 sailing
(gold) Luke Campbell 2012 boxing
Saints:
6 saints, 1 blessed
Saint Luke the Evangelist ?-84
Saint Luke Thaumaturgus ?-946
Blessed Luke Belludi 1200-1285
Saint Luke Kirby 1549-1582
Saint Luke Kiemon ?-1627
Saint Luke Loan ?-1840
Saint Luke Banabakiutu ?-1886