As an English name, Caleb came into use after the Protestant Reformation. It was common among the Puritans, who introduced it to America in the 17th century.
Due to the renown of the saint, this name has been widely used in the Christian world. It has been common in England since the 12th century, though it became a bit less popular after the Protestant Reformation. The name has been borne by five popes and two czars of Russia.
The name was brought to public attention by Samuel A. Taylor's play Sabrina Fair (1953) and the movie adaptation Sabrina that followed it the next year. This is also the name of a comic book character, Sabrina the Teenage Witch, first introduced 1962 and with television adaptations in 1970-1974 and 1996-2003, both causing minor jumps in popularity. Another jump occurred in 1976, when it was used for a main character on the television series Charlie's Angels.