Isaac   (m)  
Biblical Characters   Gen. 21:1
Isaac of Constantinople   (m)   ?-410  
Saints
Isaac of Spoleto   (m)   ?-550  
Saints
Isaac I   (m)   6xx-692  
Coptic Popes and Patriarchs of Alexandria   690-692
Isaac of Cordoba   (m)   824-851  
Saints
Isaac Comnenus   (m)   c. 1007-1061  
Roman and Byzantine Emperors   1057-1059
Isaac Angelus; Isaac II Angelus   (m)   1156-1204  
Roman and Byzantine Emperors   1185-1195; 1203-1204
Isaac Newton   (m)   1642-1727  
Notable Philosophers and Thinkers
Notable Scientists and Inventors
Adolphe Crémieux   (a.k.a. Isaac)   (m)   1796-1880  
Notable Politicians and Statespeople
Isaac Singer   (m)   1811-1875  
Notable Scientists and Inventors
Isaäc Dignus Fransen van de Putte   (m)   1822-1902  
Dutch Prime Ministers   1866
Isaac Levitan   (m)   1860-1900  
Notable Artists
Isaac Albéniz   (m)   1860-1909  
Notable Musicians
Chief John Big Tree   (a.k.a. Isaac)   (m)   1877-1967  
Notable Actors and Entertainers   (actor)
Isaac Bentham   (m)   1886-1917  
Olympic Medalists   1912   water polo   (gold)
James Wendell   (a.k.a. Isaac)   (m)   1890-1958  
Olympic Medalists   1912   110 m hurdles   (silver)
Isidor Isaac Rabi   (m)   1898-1988  
Nobel Prize Winners   1944   (physics)
Notable Scientists and Inventors
Isaac Bashevis Singer   (m)   1902-1991  
Nobel Prize Winners   1978   (literature)
Notable Writers
Isaac Asimov   (m)   1920-1992  
Notable Writers
Sid Caesar   (a.k.a. Isaac)   (m)   1922-2014  
Emmy Award Winners   1952; 1957   ; Caesar's Hour   (actor)
Notable Actors and Entertainers   (actor)
Jerry Stiller   (a.k.a. Isaac)   (m)   1927-2020  
Notable Actors and Entertainers   (actor/comedian)
Jerome Isaac Friedman   (m)   1930-  
Nobel Prize Winners   1990   (physics)
Notable Scientists and Inventors
Don Everly   (a.k.a. Isaac)   (m)   1937-2021  
Notable Musicians
Rock and Roll Hall-of-Famers   1986  
Isaac Hayes   (m)   1942-2008  
Notable Musicians
Rock and Roll Hall-of-Famers   2002  
Viv Richards   (a.k.a. Isaac)   (m)   1952-  
Notable Athletes   (cricket)
Isaac Herzog   (m)   1960-  
Israeli Presidents and Prime Ministers   2021-   (president)
Zack Brady   (a.k.a. Isaac)   (m)  
Fictional Characters from Television   1965   Days of Our Lives
Liev Schreiber   (a.k.a. Isaac)   (m)   1967-  
Notable Actors and Entertainers   (actor)
Isaac Bruce   (m)   1972-  
Hall-of-Famers   2020   (football)
Oscar Isaac   (m)   1979-  
Notable Actors and Entertainers   (actor)
Isaac Boss   (m)   1980-  
Notable Athletes   (rugby)
Isaac Hanson   (m)   1980-  
Notable Musicians
Isaac Slade   (m)   1981-  
Notable Musicians
Isaac Makwala   (m)   1985-  
Olympic Medalists   2020   4x400 m relay   (bronze)
Isaac   (m)  
Hurricanes and Tropical Storms   1988   (storm)
Isaác Brizuela   (m)   1990-  
Notable Athletes   (soccer)
Isaac Hempstead-Wright   (m)   1999-  
Notable Actors and Entertainers   (actor)
Isaac   (m)  
Hurricanes and Tropical Storms   2000   (hurricane)
Isaac   (m)  
Hurricanes and Tropical Storms   2006   (hurricane)
Isaac Mendez   (m)  
Fictional Characters from Television   2006   Heroes
Isaac   (m)  
Hurricanes and Tropical Storms   2012   (hurricane)
Isaac   (m)  
Hurricanes and Tropical Storms   2018   (hurricane)