In the English-speaking world this name is more commonly given to girls. This is due to the American actress Alexis Smith (1921-1993), who began appearing in movies in the early 1940s. It got a boost in popularity in the 1980s from a character on the soap opera Dynasty.
Due to the popularity of the saint, the name became common in the Christian world during the Middle Ages. The Normans brought it to England, where it was commonly spelled Cecily — the Latinate form Cecilia came into use in the 18th century.
In the United States this form was much less common than Isabel until the early 1990s, when it began rapidly rising in popularity. It reached a peak in 2009 and 2010, when it was the most popular name for girls in America, an astounding rise over only 20 years.
A famous bearer is the Italian actress Isabella Rossellini (1952-).
Before 1980, this was an uncommon masculine name in America. During the 1980s and 90s this name steadily increased in popularity for both boys and girls, and from 2003 onwards it has been more common for girls in the United States. Elsewhere in the English-speaking world, such as the United Kingdom and Australia, it has remained largely masculine.
This name was common among continental European royalty during the Middle Ages, and it was popularized in Britain by the German House of Hanover when they inherited the British throne in the 18th century. It was the name of characters in the novels Tom Jones (1749) by Henry Fielding and The Vicar of Wakefield (1766) by Oliver Goldsmith.
In the United States this name was only moderately common until the 1990s when it began rising in popularity, eventually becoming the most popular for girls from 2011 to 2013. A famous bearer is the Italian actress Sophia Loren (1934-).