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Manoel (1697-1736) was the son of King Pedro II of Portugal and his second wife Marie Sophie.
Manoel (1531-1537) was the son of King Joao III of Portugal and his wife Katharina of Austria.
Manoel (1889-1932) was the son of King Carlos I of Portugal and his wife Marie Amelie. He later became Manoel II, last King of Portugal.
Manoel of Portugal (1640-1640), son of King Joao IV of Portugal and his wife Luisa de Guzman.

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