In George Eliot's book "Silas Marner", it was Silas' mother's name. He named the beautiful young girl he took into care Hephzibah and nicknamed her Eppie.
-- Anonymous User 10/24/2006
In the Harry Potter books, Tom Riddle visited an old woman named Hephzibah Smith. He killed her and then stole a locket and a golden cup from her.
As well as referring to the mother of Mannaseh (2 Kings 21:1) the name is also used to refer to the people of Israel (Isaiah 62:4) as a people in whom God delights.
I thought this name was always pronounced "HEP-zi-bah", regardless of whether it is spelled with an "h" after the "p" or not. Perhaps "HEF-zi-bah" comes from too many uninformed people reading the name phonetically.