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It is a derivative of the Greek name Pantaleon, which roughly translates as "all lion". My Gr-Gr-Grandfather's name was Pantaleone Rugito - and his surname may have originally been Ruggito, which is Italian for "roar", so his birth name literally means "all lion roar". He must have had quite a cry as a baby.
Italian Pronunciation of "Pantaleone": Pahn-Tah-Leyh-Ohn-Eyh"A" as in "Father" (for both). "E" is quite close to the English greeting "Hey" (granted that the "H" is removed). "O" as usual, "Oh." And once again "E," or otherwise "Eyh." [noted -ed]
I can't believe this is very common. It's probably too close to the word "pantaloni", trousers.

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