Fortune is the alias of a character in the Metal Gear series. Her real name is Helena Dolph Jackson. She got the name for her ability to deflect bullets and render explosives inert.
Fortune Feimster is a hilarious comedian born in 1980. I joined just to post that. But then when I looked her up to make sure I spelled it right, I found out that her full name is actually Emily Fortune Feimster. So thus, that. She does use the name Fortune in her professional life!