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Opaline Deveraux Wadkins (1912–2000) was an American nurse and civil rights activist. She organized the first school to train black nurses in Oklahoma City, fought for desegregation of the College of Nursing at the University of Oklahoma and founded the School of Nursing at Langston University. She was the first African American nurse to earn a master's degree from the University of Oklahoma. She was honored in 1987 by the Oklahoma Public Health Association and inducted into the Oklahoma Women's Hall of Fame in 1993.

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