Perhaps intended to be a feminine form of SAMUEL, using the name suffix antha (possibly inspired by Greek ανθος (anthos) "flower"). It originated in America in the 18th century but was fairly uncommon until 1964, when it was popularized by the main character on the television show 'Bewitched'.

Baccano characters, Big Little Lies characters, flowers, nature, plants, Star Trek characters, Stephen King characters, Tiger and Bunny characters, top 10 in the US, trendy, witches